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diabetes inhibitors agonists allopurinol anthracycline based cardiotoxicity combo estimation glp1 gout her2 insulin management oncology oral pills renal summary tablets
Diabetes Combination Tablets - Estimated A1c Lowering Metformin + DPP4 • Janumet (metformin + sitagliptin) •
Diabetes Combination ... Metformin + DPP4 ... Tablets #Oral #DM2 ... #Pharmacology # ... Pills #Endocrinology
DPP-4 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
- Pharmacology ... Recommended to avoid combination ... #Inhibitors #Pharmacology ... #Summary #DM2 # ... diabetes #endocrinology
DPP4 Inhibitors - Normal and Renal Dosing Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Normal and Renal Dosing ... Inhibitors #Renal #Dosing ... #Pharmacology # ... Management #Diabetes #DM2 ... #Endocrinology
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing TDD in units of insulin = N
: Weight-Based Dosing ... glucocorticoids, or combination ... Weight #Based #pharmacology ... #endocrinology ... #diabetes #DM2
GLP-1 Agonists Adlyxin (Lixisenatide) Daily Bydureon (Exenatide ER) Weekly Ozempic (Semaglutide) Weekly Trulicity (Dulaglutide) Weekly Victoza (Liraglutide) Daily
very similar to DPP4s ... GLP1 #Agonists #Pharmacology ... #Dosing #Diabetes ... #DM2 #Endocrinology
Allopurinol Pharmacology Summary Xanthine oxidase inhibitor blocking the formation of new uric acid Initiate 1-2 days prior to
Allopurinol Pharmacology ... days prior to chemotherapy ... Dosing: 100 mg ... /m2/dose every 8 ... #pathophysiology
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity Anthracyclines cause cardiomyopathy: ✖ Reduction in left ventricular ejection fraction
, 350 mg/m2, and ... every 3 months during ... Cardiotoxicity #cardiology ... #oncology #pharmacology ... #toxicity #chemotherapy
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