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oncology leukemia hodgkins joint lymphocytic lymphoma msk pain algorithm approach classification cold differentiation erythematosus gap globulin hemeonc immunecompromised immunocompromised lupus
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... -> AML: Blast crises ... pain, bleeding, infections ... bruising, bleeding, infection ... #Leukemia #Hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
e.g., HIV), EBV infection ... - Pel-Ebstein fever ... Etiology: - Infections ... Diagnosis of B-Symptoms ... hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... Pseudogout) • Infectious ... Infection • ... joints Viral Infections ... #rheumatology #
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm Structural Defect - Asplenia/HypospIenism • Bacteremia/Septic
Causes of Fever ... jirovecii • CNS Infection ... • Perirectal Infection ... Diarrhea • Giardia Infection ... #Causes #Hematology
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
decades of life Causes ... Infections 2. ... Autoimmune diseases ... - Headache, fever ... #rheumatology #
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... → fevers, night ... Complications: 1) Infection ... Leukemia #oncology #hematology ... #management
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
about bacterial infections ... about indolent infections ... with bacterial infection ... Joint #Pain #MSK #rheumatology ... diagnosis #arthritis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Lymphadenopathy • Fevers ... weeks without infection ... #workup #oncology ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
: >3 symptoms, or ... initiation • Differential ... Diagnosis: Infection ... #diagnosis #management ... #hematology #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... fibromyalgia) • Infections ... Induced Lupus: • Symptoms ... with Lupus: • Chronic ... #Rheumatology
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