246 results
Endotypes and mechanisms involved in anaphylaxis. 

#anaphylaxis #Endotypes #pathophysiology
Endotypes and mechanisms ... #anaphylaxis #Endotypes
Monkeypox - Virology

Causative Agent: Monkeypox virus (MPV)
Year of Discovery: 1958
Genome: Double-stranded DNA
Variants and Genotypes: 2 clades
Primary
Monkeypox virus (MPV ... Variants and Genotypes ... #MPX #MPV #monkeypox
ANCA-Associated Vasculitis
A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
polyangiitis (MPA ... associated with MPO ... polyangiitis - MPO ... polyangiitis - MPO ... #CANCA #PANCA #MPO
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
C-ANCA): GPA >>> MPA ... > eGPA • MPO-ANCA ... P-ANCA): eGPA, MPA
Volume Assist/Control Mechanical Ventilation
How does this mode work?
 • Delivers a set volume of air with
receives a minimum MV ... Protective Ventilation (LPV ... ) • PRVC mav have ... need to monitor MV ... pre-intubation MV
Fungal Biomarkers: Comparing Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 •
Spec -80% for IA, PPV ... < 50%, NPV > 90%
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Diagnosis Framework by MCV ... Microcytic (MCV ... Normocytic (MCV ... Macrocytic (MCV ... MatthewHoMD #Anemia #MCV
Important Biostatistics and Epidemiology Equations

Sensitivity = TP / (TP + FN) = true positives / disease
#specificity #PPV ... #NPV
Radiation Dose to Adults from Common Imaging Examinations
ABDOMINAL REGION
 - Computed Tomography (CT) — Abdomen and
and Pelvis 10 mSv ... Colonography 6 mSv ... With Barium 6 mSv ... X-ray 0.001 mSv ... (CT) — Head 2 mSv
ANCA Associated Vasculitis (AAV) - Auto-antibodies and Differential Diagnosis

MPA → usually p-ANCA
GPA → usually c-ANCA
EGPA →
Differential Diagnosis MPA ... 50% P-ANCA (MPO