14 results
This image shows portions of glomerular tuft with collapsed GBM (across top), spicular amyloid (middle right),
with collapsed GBM ... top), spicular amyloid ... #glomerulus #GBM ... SEM #clinical #nephrology ... #pathology
Causes of acute kidney injury (AKI). AKI is classified into pre-renal, renal, and post-renal causes. Renal
Causes of acute ... and interstitial disease ... GBM, Glomerular ... Diagnosis #AKI #Acute ... Causes #Sites #Nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
Acute Kidney Injury ... Immune-complex disease ... , Anti-GBM • Tubular ... Bilateral ureteral disease ... Differential #Diagnosis #nephrology
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
selected glomerular diseases ... Minimal change disease ... Membranous GN • Amyloid ... RPGN • Anti-GBM ... #nephrology #pathology
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
Syphilis, Lyme disease ... myeloma, secondary amyloid ... Charcot-Marie-Tooth, Fabry's disease ... , Acute intermittent ... diagnosis #causes #neurology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
ANCA-positive vasculitis (Eosinophilic ... vasculitis, Behcet disease ... Goodpasture's Disease ... anti-ANCA ab, anti-GBM ... differential #diagnosis #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... ANCA, ANA, Anti-GBM ... Interstitial nephritis: eosinophilia ... cardiac imaging #Acute ... Differential #Diagnosis #nephrology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... extramedullary disease ... cells - Blood & BM ... • Cytopenia -> BM ... • (Peripheral eosinophilia
B-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Clinical
 - Primarily a disease of childhood, 75% <6 yo
 - Increased
B-Cell Acute Lymphoblastic ... - Primarily a disease ... extramedullary disease ... with limited BM ... Lymphoma #hemepath #pathology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
- Systemic disease ... Streptococcal (28%) - Gm ... Mycobacterium (8%) - Gm ... Reactive Syndrome - Acute ... Osteosarcoma - Eosinophils