16 results
This image shows portions of glomerular tuft with collapsed GBM (across top), spicular amyloid (middle right),
with collapsed GBM ... #glomerulus #GBM ... #deposits #ElectronMicroscopy ... SEM #clinical #nephrology ... #pathology
This image shows spicular amyloid deposits showing blunt conical formations with interconnecting fibrils.

Dr. Stephen Bonsib via
shows spicular amyloid ... deposits showing ... arkanalabs #amyloid ... SEM #clinical #nephrology ... #pathology #renal
This image shows spicular amyloid with tapering conical masses interconnected by branching fibrils!

Dr. Stephen Bonsib via
shows spicular amyloid ... arkanalabs #amyloid ... #desposition #deposits ... SEM #clinical #nephrology ... #pathology
Kidney Biopsy - Diagnosis Algorithms
1) Normal Glomerulus by LM
2) Glomerular Crescents
3) Double Contours of GBM
4) Endocapillary
Kidney Biopsy - Diagnosis ... Double Contours of GBM ... Biopsy #renal #Diagnosis ... #Algorithm #nephrology ... #pathology
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
Basement Membrane (GBM ... Linear, ribbon-like GBM ... Minimal immune deposits ... #Differential #Diagnosis ... #Nephrology
This image shows glomerular tuft with overall intact architecture. Discrete masses of specular amyloid interrupt smooth
masses of specular amyloid ... CapillaryLoop #glomerulus #amyloid ... #desposition #deposits ... SEM #clinical #nephrology ... #pathology
This image shows a glomerular tuft with overall intact architecture. Discrete masses of specular amyloid (long
masses of specular amyloid ... #glomerulus #amyloid ... #desposition #deposits ... SEM #clinical #nephrology ... #pathology
Glomerulonephritis - Differential Diagnosis Framework
ANCA:
 • C-ANCA: GPA (Wegener's)
 • P-ANCA: Microscopic Polyangiitis, Eosinophilic GPA (Churg
- Differential Diagnosis ... Polyangiitis, Eosinophilic ... Strauss) Anti-GBM ... #differential #diagnosis ... #nephrology #causes
ANCA-Associated Vasculitis
A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
lack of immune deposits ... polyangiitis (MPA), and eosinophilic ... polyangiitis - MPO>PR3 Eosinophilic ... rarely PR3 Anti-GBM ... PANCA #MPO #PR3 #Diagnosis
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... ANCA-positive vasculitis (Eosinophilic ... anti-ANCA ab, anti-GBM ... #differential #diagnosis ... #nephrology