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Differential Diagnosis of Pulmonary Eosinophilia Infection: • Helminthic: Loffler syndrome (Ascaris, hookworm, Strongyloides), Tropical pulmonary eosinophilia (lymphatic
Differential Diagnosis of Pulmonary ... Helminthic: Loffler syndrome ... Acute chronic pulmonary ... syndrome, Neoplasms ... #Pulmonary #Differential
Approach to Eosinophilic Lung Diseases • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
Approach to Eosinophilic ... Diseases • Acute Eosinophilic ... SOB • Chronic Eosinophilic ... Hypereosinophilic Syndrome ... Lung #Diseases #pulmonary
Small Vessel Vasculitides • Granulomatosis with polyangiitis - Granulomatous manifestations (e.g., nasal crusting, destructive sinusitis, pulmonary
destructive sinusitis, pulmonary ... lung disease • Eosinophilic ... polyangiitis - Asthma. eosinophilia ... and Sjogren's syndrome
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... Syndrome Definition ... Presentation (Pulmonary ... Renal Syndromes ... ANCA-positive vasculitis (Eosinophilic
Interstitial Lung Diseases (ILD) Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): • Hypersensitivity pneumonitis, Farmer's lung, Bird
• Idiopathic pulmonary ... polyangiitis, Eosinophilic ... Churg Strauss syndrome ... ) • Eosinophilic ... #differential #pulmonary
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager ... polyangiitis), EGPA (eosinophilic ... Renal Syndromes ... differential (check eosinophil ... #Renal #Syndromes
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
GI - Felty syndrome ... • Felty's syndrome ... Wilson's disease Pulmonary ... Spondyloarthropathies, SLE • Pulmonary ... Amyloidosis • Eosinophilic
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
rarely present with eosinophilic ... solitary and multiple pulmonary ... respiratory distress syndrome ... pneumonia - Pulmonary ... Neutrophilia • Eosinophilia
Eosinophilic Pneumonia When to suspect Eosinophilic Pneumonia? Non-resolving pneumonia + BAL > 25% eosinophils + excluded more
Eosinophilic Pneumonia ... When to suspect Eosinophilic ... diagnoses Acute Eosinophilic ... Consolidations AKA "inverse pulmonary ... Pneumonia #diagnosis #pulmonary
Eosinophilia - Differential Diagnosis Algorithm Idiopathic Eosinophilia Primary Eosinophilia: • Primary hypereosinophilic syndrome • Eosinophilic Leukemia • MPN/MDS
hypereosinophilic syndrome ... • Eosinophilic ... Hyper-lgE (Job) syndrome ... ABPA), Gleich syndrome ... Infectious: Loeffler syndrome
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