11 results
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Primary Metabolic ... Urine Cl-: Vomiting ... , Gitelman Syndrome ... hyperaldosteronism • High PRA: Renal ... #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... Urine Cl-: Vomiting ... , Gitelman Syndrome ... hyperaldosteronism • High PRA: Renal ... #Nephrology #Causes
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Extra-renal Losses ... intake • Metabolic ... loss (Diarrhea) Renal ... , Gitelman syndrom ... #nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
A urine K/Cr ratio ... suggests extra-renal ... , Gitelman syndrome ... differential #potassium #nephrology ... #low
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... Urine Cl-: Vomiting ... , Gitelman Syndrome ... hyperaldosteronism • High PRA: Renal ... #Nephrology #Causes
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Causes of Metabolic ... Chloridorrhea Renal ... Hypomagnesemia • Barrter's/Gitelman's ... Licorice • Liddle's Syndrome ... MetabolicAlkalosis #NonGap #Nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Urinary Chloride Algorithm ... alkalosis • Normal/low ... diuretic use, Bartter syndrome ... , Gitelman syndrome ... #Algorithm #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Injury - AKI Workup Algorithm ... microscopy / urinary sediment ... investigations depending on clinical ... syndrome: troponin ... Differential #Diagnosis #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... tubule (DCT) Clinical ... alkalosis • Normal or low ... Hypocalciuria (spot urine ... #nephrology #management
Gitelman Syndrome - Diagnosis and Workup
Blood Work:
 - Hypokalemia
 - Hypomagnesemia
 - Metabolic Alkalosis
 - Elevated
Gitelman Syndrome ... Hypomagnesemia - Metabolic ... Elevated Renin Urine ... excretion of Cl > 0.5% Clinical ... #Workup #nephrology