11 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
the critically ill ... Elevated Liver tests ... #AFLP #obstetrics ... #hematology #diagnosis ... #table #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
the critically ill ... Elevated Liver tests ... #AFLP #Obstetrics ... #Diagnosis #Comparison ... #Table
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... not required in all ... #Causes #Workup ... #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
adults in the west ... lymphoproliferative disorders ... Neutropenia, anemia, thrombocytopenia ... #workup #oncology ... #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Consider sickle cell ... Schistocytes, thrombocytopenia ... - DIC, TTP, HELLP ... Consider RBC membrane disorder ... #Algorithm #workup
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... coagulation (DIC) - HELLP ... microangiopathy: Thrombotic thrombocytopenic ... ) (e.g. lupus, CLL ... lymphoproliferative disorders
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
MYH9-Related Disorder ... structure and cell ... Defects #comparison #table ... #differential #diagnosis ... #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... for All Types of ... metabolic or endocrine disorders ... #diagnosis #testing ... #Rheumatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... platelet count (thrombocytopenia ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Better call hematology ... you’ll do a good workup ... Best to have an ... expert around to help ... #Algorithm #workup