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diagnosis rheumatology differential vasculitis classification lupus algorithm ana antibodies antinuclear aortitis arthritis cryoglobulinemia cryoglobulins dermatology disease druginduced joint laboratory management
ANCA-Associated Vasculitis There are many definitions, but most come down to the presence of granulomas (pathologically or
ANCA-Associated ... pathologically or clinically ... polyangiitis (GPA ... differential #diagnosis #algorithm ... #rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Malar rash • SLE ... Vesicopustule on erythematous ... Amyloidosis • Eosinophilic ... Sarcoidosis • GPA ... Discoid lupus erythematosus
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
(GCA), Takayasu's ... Nodosa (PAN), ANCA ... Systemic lupus erythematosus ... (SLE), Sarcoidosis ... Differential #Diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
• EGPA: - Eosinophilia ... ischemia - Skin: erythematous ... and branches • GCA ... systemic lupus erythematosus ... vasculitis, and SLE
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Suspect: Clinical ... macular, patchy eruption ... Diagnosis: • ANCA-associated ... Malignancy (e.g. hematologic ... vein thrombosis Hematologic
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... Systemic lupus erythematosus ... Juvenile Idiopathic Arthritis ... Systemic lupus erythematosus ... #patterns #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms, Arthritis ... Systemic Lupus Erythematosus ... #comparison #table ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... Elevated ESR and CRP GCA ... develop in pts with GCA ... ischemia • Skin: Erythematous ... Polyangiitis): • Eosinophilia
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Systemic lupus erythematosus ... ACE level, CXR, ANCA ... and RF (if clinical ... diagnosis #testing #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... diseases: - 10% SLE ... DDX: • ANCA (Antineutrophil ... systemic lupus erythematosus ... (SLE), rheumatoid
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