8 results
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... Epithelial cell casts ... Glomerulonephritis • Anti-GBM antibodies ... lupus, sarcoid, Sjögren ... Diagnosis #Algorithm #Causes
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... Anti-dsDNA (in 70% of cases ... seen in 30—70% of cases ... • Sjögren syndrome ... Antineutrophil #antibodies
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Vasculitis (lupus, RA, Sjogren's ... of antinuclear antibodies ... antineutrophil cytoplasmic antibodies ... Diagnosis #Algorithm #Causes
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... enlargement Sjogren's ... hypofunction • Antibodies ... • Antinuclear antibodies ... Hypocomplementemia • Can cause
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Autoimmune: thyroid, Sjogren ... Labs: - AchR antibodies ... assay - MuSK antibodies ... - LRP4 antibodies ... Myasthenia Crises
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
: • 1400 new cases ... for NMO, SLE or Sjogren's ... • Infectious causes ... Bechet disease - Sjogren ... Antiamphiphysin antibodies
Celiac disease is an immune-mediated, multisystem disorder that affects genetically susceptible individuals who are exposed to
diseases (mainly Sjogren ... The two antibodies ... transglutaminase antibodies ... anti-endomysial antibodies ... performed in select cases
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
hearing loss, nausea ... diseases 30% of cases ... Most common • Sjogren ... Anti-Matrilin-1 Ab ○ Antibodies