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diagnosis rheumatology differential dermatology systemic vasculitis cerebritis classification cns common cord cryoglobulins cvid diuresis diuretics erythematosus excretion fatigue gravis hypogammaglobulinemia
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... • Autoimmune diseases ... syndrome) #Cryoglobulinemia ... classification #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... vasculitis/HSP • Cryoglobulinemia ... Associated - SLE, Sjogren's ... Differential #Diagnosis #hematology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Neoplastic / Hematologic ... Obstructive Pulmonary Disease ... Neurologic • ... • Somatization Disorder ... Fatigue Syndrome
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... discoloration) • Chronic ... • Nephrotic syndrome ... Differential #Diagnosis #Algorithm ... #causes
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Nephrogenic DI Hematologic ... Vasculitis: • 7%, Cryoglobulinemia ... #Syndrome #Rheumatology ... #Diagnosis #Management
Oral / Mouth Lesions and Ulcers (Adult & Elderly) - Differential Diagnosis Algorithm Teeth • GERD (Dissolves
Syndrome (Dental ... Colour Change • Chronic ... • Sjögren's Syndrome ... #Oral #Mouth #Disorders ... #Causes
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... autoantibodies that will cause ... Erythematosus #SLE #CNS #neurology ... cerebritis #diagnosis #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... Autoimmunity • Chronic ... DDX - Other causes ... : • Nephrotic syndrome ... hypogammaglobulinemia #immunology #hematology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
disequilibrium syndrome ... irrigation • Management ... Kidney stones caused ... specific bleeding disorders ... Excretion #Diuresis #Nephrology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
an autoimmune disorder ... Autoimmune: thyroid, Sjogren ... inhibition - Chronic ... Gravis #diagnosis #management ... #neurology
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