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diagnosis rheumatology differential dermatology systemic vasculitis cerebritis chronic classification cns cord cryoglobulins erythematosus fatigue gravis lupus myasthenia myelitis naildisorders nonpalpable
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... • Autoimmune diseases ... : - 10% SLE or ... syndrome) #Cryoglobulinemia
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Splenomegaly - CTD (SLE ... Kasabach-Merritt syndrome ... vasculitis/HSP • Cryoglobulinemia ... Associated - SLE ... , Sjogren's
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Neoplastic / Hematologic ... Arthritis • SLE ... Neurologic • ... • Somatization Disorder ... Chronic Fatigue Syndrome
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... autoantibodies that will cause ... #CNS #neurology ... cerebritis #diagnosis #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... overlaps with RA, SLE ... Nephrogenic DI Hematologic ... #Syndrome #Rheumatology ... #Diagnosis #Management
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... Abnormality • SLE ... • Nephrotic syndrome ... Differential #Diagnosis #Algorithm ... #causes
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
or Sjogren's ... • Infectious causes ... - Sjogren - ... Myelitis #diagnosis #management ... #neurology #differential
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Sarcoidosis, Behcet disease ... - SLE, Scleroderma ... syndrome Cord ... #diagnosis #neurology ... differential #algorithm
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
an autoimmune disorder ... Autoimmune: thyroid, Sjogren ... arthritis, SLE ... Gravis #diagnosis #management ... #neurology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, such as SLE, atherosclerotic ... affects the skin, neurologic ... cognitive impairment, neurologic ... tract, and often causes ... / ANCA + MPO) Cryoglobulinemic
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