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diagnosis rheumatology differential cerebritis chronic classification cns cord cryoglobulins dermatology erythematosus fatigue nonpalpable palpable polychondritis purpura relapsing spinal spinalcord systemic
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... • Autoimmune diseases ... : - 10% SLE or ... (e.g. systemic lupus ... syndrome) #Cryoglobulinemia
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Splenomegaly - CTD (SLE ... Kasabach-Merritt syndrome ... vasculitis/HSP • Cryoglobulinemia ... Associated - SLE ... , Sjogren's
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... autoantibodies that will cause ... #CNS #neurology ... cerebritis #diagnosis #management
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Neoplastic / Hematologic ... Arthritis • SLE ... Neurologic • ... • Somatization Disorder ... Chronic Fatigue Syndrome
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... overlaps with RA, SLE ... Nephrogenic DI Hematologic ... #Syndrome #Rheumatology ... #Diagnosis #Management
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Sarcoidosis, Behcet disease ... - SLE, Scleroderma ... syndrome Cord ... #diagnosis #neurology ... differential #algorithm
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
including systemic lupus ... erythematosus (SLE ... ), Sjögren’s syndrome ... TAFRO #diagnosis #management ... #rheumatology #
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
body (Autoimmune disorder ... as: • SLE • RA ... Most common • Sjogren ... Sarcoidosis • Behcet disease ... #diagnosis #management
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