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diagnosis rheumatology differential lupus sle cerebritis inflammatory manifestations myelitis neuromyelitis nmo optica signs syndromes tafro thrombocytopenia transverse treatment vasculitis
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
BEE Syndromes - ... (CNS) involvement ... • Sjögren syndrome ... erythematosus ... #Syndromes #neurology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
pain • Extra-CNS ... (Systemic lupus ... erythematosus, ... Sjögren syndrome ... #symptoms #signs
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... autoantibodies that will cause ... #SLE #CNS #neurology ... cerebritis #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... dermatomyositis, Sjogren ... and CNS • Headache ... APLA/LAC: • Renal ... Induced Lupus: • Symptoms
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... 6th Decades (can be ... Hypocomplementemia • Can cause ... Distal (Type I) renal ... #Diagnosis #Management
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... Bilateral signs and/or symptoms ... • Infectious causes ... Myelitis #diagnosis #management ... #neurology #differential
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulmonary and renal ... Symptoms (SX) in ... ischemia • Skin: Erythematous ... tract, and often causes ... chorioretinitis, CNS
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
lupus erythematosus ... (SLE), Sjögren’ ... symptoms Histopathological ... is thought to be ... TAFRO #diagnosis #management
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