10 results
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... Antineutrophil cytoplasmic antibodies ... in drug-induced SLE ... • Sjögren syndrome ... #diagnosis #rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... overlaps with RA, SLE ... Distal (Type I) renal ... #Syndrome #Rheumatology ... #Diagnosis #Management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... autoantibodies that will cause ... #CNS #neurology ... #rheumatology #
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
dermatomyositis, Sjogren ... syndrome, and mixed ... Non-autoimmune rheumatologic ... and CNS • Headache ... APLA/LAC: • Renal
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
autoimmune disorder ... Autoimmune: thyroid, Sjogren ... arthritis, SLE ... Gravis #diagnosis #management ... #neurology
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Acid Base Disorders ... D-lactate (short bowel syndrome ... acidosis: - CNS ... restrictive lung disease ... MDaniyalHashmi1 #AcidBase
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... or Sjogren's ... Antiamphiphysin antibodies ... Myelitis #diagnosis #management ... #neurology #differential
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
renal abnormalities ... , such as SLE, atherosclerotic ... often causes arthritis ... chorioretinitis, CNS ... Differential #Diagnosis #Rheumatology
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
erythematosus (SLE ... ), Sjögren’s syndrome ... histopathologic changes in LNs ... TAFRO #diagnosis #management ... #rheumatology #
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
body (Autoimmune disorder ... as: • SLE • RA ... Most common • Sjogren ... Heart failure • Renal ... #diagnosis #management