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diagnosis dermatology systemic nephrology anemia classification erythematosus lupus pruritus secondary sle treatment vasculitis abg acid acidbase approach base basophilia basophils
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... / Bruising - Differential ... Diagnosis Algorithm ... ASA) • Renal Disease ... #Causes #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Kasabach-Merritt syndrome ... Associated - SLE, Sjogren's ... #Diagnosis #hematology ... #rheumatology #
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Metabolic • Renal ... Neoplastic / Hematologic ... Neurologic • ... • Somatization Disorder ... Fatigue Syndrome
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Chain deposition disease ... autoimmune (RA, Sjogren's ... antiphospholipid syndrome ... #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm ... RBCs on Smear • Chronic ... Bleed - Any combination ... Disease • Marrow ... #Causes #Hematology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... renal failure ... #Differential # ... Diagnosis #Algorithm ... #causes
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
- Systemic and ... Primary Causes ... Creatinine & BUN: • Chronic ... renal failure/uremia ... Myelodisplastic syndrome
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... • Rule out B12 and ... #Causes #Hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Basophilia - Differential ... Myeloproliferative Disorders ... : • Chronic myeloid ... Crohn’s Disease ... #hematology #basophils
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Distal (Type I) renal ... Nephrogenic DI Hematologic ... #Syndrome #Rheumatology ... #Diagnosis #Management
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