18 results
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
lymphocytes/Mature B cell ... Hepatomegaly • Skin ... and other C Cell ... microglobulin Treatment ... workup #oncology #hematology
Seborrheic keratoses vary widely in appearance - one of the most common benign skin lesions that
common benign skin ... Key features: well ... Keratosis #Keratoses #Dermatology ... Clinical #Photo #Table
Symptoms Distinguishing Groups of Cutaneous Drug Reactions
IgE-mediated reactions:
 • Onset minutes to hours into treatment course
Raised off of the skin ... scarring Benign T-cell-mediated ... weeks Severe T-cell-mediated ... Blistering and/or skin ... Drug #Reactions #dermatology
DRESS Syndrome vs SJS/TEN
DRESS
 • Latency: 2-8 weeks
 • Rash: Morbilliform
 • Mucosal involvement: 50% have
involvement, rarely with erosions ... Tubulointerstitial nephritis • Skin ... Prerenal azotemia • Skin ... TEN #comparison #table ... #dermatology
Severe Drug Rashes - Comparison - DRESS | SJS/TEN | AGEP | Erythroderma

DRESS 
 - Onset:
mucocutaneous erosions ... >90% of total skin ... Rashes #Comparison #TABLE ... #Erythroderma #Dermatology
Scleroderma Like Conditions - Differential Diagnosis
Eosinophilic Fasciitis:
 - Orange peel induration (peau d'orange) of proximal extremities
lymphocytes, plasma cells ... the mainstay of treatment ... hematopoietic stem cell ... Diagnosis #comparison #table ... #dermatology
Eczematous Skin Rash - Differential Diagnosis Algorithm
Eczematous - Pruritic/Scaly/Erythematous lesions. Usually poorly demarcated
 • Atopic Dermatitis
Eczematous Skin ... Contact Dermatitis - Well-demarcated ... papules, vesicles, erosions ... Eczematous #SkinRash #dermatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophilia, 500-1,500 cells ... Hypereosinophilia, >1,500 cells ... glucocorticoid treatment ... symptoms (eg, skin ... Differential #diagnosis #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... factor (GCSF) treatments ... marrow studies Treatment ... Immunosuppressive treatment ... Syndromes #diagnosis #hematology
Pustular Skin Lesions - Differential Diagnosis Framework

What are pustules?
• Pustules < 5-10 mm + pus
• Material
Pustular Skin Lesions ... of inflammatory cells ... to inflammatory skin ... Erosive pustular ... Differential #Diagnosis #Dermatology