19 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... Vesicopustule on erythematous ... Antiphospholipid-antibody syndrome ... • Vasculitis ... #dermatology #joint
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pulmonary ... • Interstitial lung ... , SLE • Pulmonary ... • Shrinking lung ... , Vasculitis (e.g
Small Vessel Vasculitides
 • Granulomatosis with polyangiitis - Granulomatous manifestations (e.g., nasal crusting, destructive sinusitis, pulmonary
destructive sinusitis, pulmonary ... - Interstitial lung ... disease • Eosinophilic ... systemic lupus erythematosus ... and Sjogren's syndrome
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
ANCA-positive vasculitis ... ANCA-negative vasculitis ... IgA-associated vasculitis ... Systemic lupus erythematosus ... , Rheumatoid arthritis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
ANCA-associated vasculitis ... syndrome Arthritis ... : • Joint pain ... arthropathy • 90% joints ... and leukemia • Lung
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
ischemia - Skin: erythematous ... vesicular eruption - Joints ... : • Behçet Syndrome ... • Cogan Syndrome ... systemic lupus erythematosus
Interstitial Lung Diseases (ILD)
Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): 
 • Hypersensitivity pneumonitis, Farmer's lung, Bird
sclerosis, Rheumatoid arthritis ... • Idiopathic pulmonary ... Sarcoidosis • Vasculitis ... Churg Strauss syndrome ... #differential #pulmonary
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Butterfly rash, Vasculitis ... effusion, Restrictive lung ... of hip (rare), Arthritis ... Demyelinating syndromes ... pain (20%) Renal disease
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
interstitial lung ... PSS: Sjogren syndrome ... RA: rheumatoid arthritis ... Differential #Comparison #Table ... #Pulmonary #Rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
ischemia • Skin: Erythematous ... vesicular eruption • Joints ... Palpable purpura, joint ... • Behcet syndrome ... • Cogan syndrome