9 results
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
Differential Diagnosis Algorithm ... required • Lupus erythematosus ... #dermatology #Differential ... #Diagnosis #Algorithm ... #causes
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... : Malar rash, Photosensitivity ... , Alopecia, oral ... Positive in 60-80% of cases ... Management #Summary #rheumatology
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Mucocutaneous Manifestations ... areas -> Scaring alopecia ... hair follicles -> causes ... cells -> Incr local ... Livedo Reticularis, Vasculitis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... GPA causes disease ... Maculopapular rash ... #rash #diagnosis ... #rheumatology
Focal / Localized Hair Loss (Alopecia) - Differential Diagnosis Algorithm

Scarring - Irreversible-biopsy required
 - Infectious
Focal / Localized ... Discoid lupus erythematosus ... #Focal #Localized ... #dermatology #Differential ... #causes
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Diagnosis Algorithm ... Infection - Vasculitis ... Urinalysis • Fecal ... #Causes #dermatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... Systemic Lupus Erythematosus ... : Malar rash, Photosensitivity ... , Alopecia, oral ... comparison #table #rheumatology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
(blue-purple) rash ... with edema • Erythematous ... rash on the face ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
(blue-purple) rash ... rash on the face ... Muscle atrophy may cause ... diagnosis #management #rheumatology ... #dermatology