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diagnosis erythematosus lupus management vasculitis antinuclear autoantibodies criteria eularacr hematology macrophage mas mimickers myelitis patterns signs syndrome transverse vasculitides
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... rash • Erythematous ... alopecia Differential ... Chronic B-cell activation
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... 69% - Malar rash ... Auto-Antibodies ... : - ANA 95-100% ... Diagnosis and Lupus
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... likely it will be clinically ... (SLE), Systemic ... #rheumatology #diagnosis ... #differential
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Clinical Domains ... least 2 joints • Neurologic ... low C4, Low C3 and ... #Criteria #SLE ... #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
, such as IL-1 and ... hemophagocytosis and ... • Heart, lung, and ... [SLE], AOSD) • ... Diagnosis #Management #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... Symptoms (Sx) in ... LFT • ESR • ANA ... SLE) • Urinalysis ... #classification
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... Symptoms (SX) in ... ischemia • Skin: Erythematous ... , mucositis • Rash ... #Diagnosis #Rheumatology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... • Excessive activation ... Transverse Myelitis - Clinical ... /or symptoms • ... #differential
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