10 results
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Systemic Lupus Erythematosus ... cutaneous lupus erythematosus ... (ACLE) • Erythematous ... cutaneous lupus erythematosus ... • Erythematous
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Manifestations: - Arthritis ... 69% - Malar rash ... Systemic #Lupus #Erythematosus ... rheumatology
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
within 1 month of infection ... formation, systemic autoimmune ... Systemic Lupus Erythematosus ... should have other symptoms ... like “butterfly rash
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
Clinical Findings ... accompanies other autoimmune ... like rheumatoid arthritis ... systemic lupus erythematosus ... Sjogrens #Syndrome #Pathophysiology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... likely it will be clinically ... Systemic lupus erythematosus ... Systemic lupus erythematosus ... Systemic lupus erythematosus
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... purpuric macules • Erythematous ... • Ulcerated, erythematous ... reticularis Differential ... • Giant cell arteritis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
ischemia - Skin: erythematous ... mucositis - Rash ... systemic lupus erythematosus ... to exclude are infections ... purpura: strong sign
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... ischemia • Skin: Erythematous ... , mucositis • Rash ... • Progressive symptoms ... #Diagnosis #Rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... Diagnosis = clinical ... very remarkable w/differential ... vasculitis vs infection ... them, but urgent rheumatology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... Tenderness → Consider infectious ... : • Gottron rash ... Gottron sign) ... • Nonerosive arthritis