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diagnosis rheumatology management activation criteria cryoglobulinemia cryoglobulins dermatologic druginduced eularacr granulomatosis hematology joint laboratory macrophage mimickers pain polyangiitis rashes rheumatic
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Vesicopustule on erythematous ... Sarcoidosis • GPA ... lesions • Discoid lupus ... erythematosus ... #dermatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Erythematosus) ... rash • Erythematous ... lupus erythematosus ... #Systemic #Lupus
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... 69% - Malar rash ... Auto-Antibodies ... #Systemic #Lupus ... #Erythematosus
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Lupus Erythematosus ... Clinical Domains ... • Arthritis domain ... #Systemic #Lupus ... #Erythematosus
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... purpuric macules • Erythematous ... • Ulcerated, erythematous ... #dermatology #rash
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
ischemia - Skin: erythematous ... mucositis - Rash ... disease Differential ... , such as systemic ... lupus erythematosus
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... months to years) Systemic ... Lupus Erythematosus ... Evolution: Chronic disease ... #sle #comparison
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... • Autoimmune diseases ... - GPA, EGPA, microscopic ... lupus erythematosus ... diagnosis #types #classification
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... erythematosus ... Petechial or purpuric rash ... lupus erythematosus ... [SLE], AOSD) •
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... as SLE, atherosclerotic ... ischemia • Skin: Erythematous ... , mucositis • Rash ... disease #Vasculitis
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