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diagnosis rheumatology lupus joint activation arthropathy criteria cryoglobulinemia cryoglobulins dermatologic disorders eularacr gpa granulomatosis hematology macrophage management mas monoarthritis monoarticular
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... Vesicopustule on erythematous ... Discoid lupus erythematosus ... #dermatology ... #skin #rashes #differential
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
Diagnosis Algorithm ... Lupus Erythematosus ... (SLE), should have ... like “butterfly rash ... #arthropathy #arthropathies
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Erythematosus) ... (ACLE) • Erythematous ... rash • Erythematous ... #Erythematosus
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... of hip (rare), Arthritis ... #systemic #erythematosus
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Lupus Erythematosus ... Clinical Domains ... cutaneous lupus • Arthritis ... #Criteria #SLE ... #Erythematosus
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
ischemia - Skin: erythematous ... mucositis - Rash ... lupus erythematosus ... , and SLE) • Urinalysis ... #rheumatology #classification
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... purpuric macules • Erythematous ... • Ulcerated, erythematous ... reticularis Differential ... • Giant cell arteritis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... Syndrome: • Clinical ... lupus erythematosus ... (SLE), rheumatoid ... diagnosis #types #classification
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... diseases, such as SLE ... affects the skin, neurologic ... ischemia • Skin: Erythematous ... , mucositis • Rash
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lupus erythematosus ... Fever is the main clinical ... Petechial or purpuric rash ... lupus erythematosus ... [SLE], AOSD) •
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