21 results
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
BEE Syndromes - ... central nervous system ... erythematosus ... #Syndromes #neurology ... differential #diagnosis
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
clinically significant ... SLE), Sjogren's Syndrome ... Drug-Induced, Inflammatory ... ANA #patterns #rheumatology ... #diagnosis #differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Suspect: Clinical ... photosensitivity, inflammatory ... Classification: ... permanent alopecia Differential ... Clinical Features
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Demyelinating syndromes ... pain (20%) Renal disease ... #erythematosus ... #signs #symptoms
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
(SLE) Clinical ... Demyelinating Syndrome ... Cerebrovascular Disease ... #SLE #CNS #neurology ... #rheumatology #
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
erythematosus ... Petechial or purpuric rash ... lupus erythematosus ... #Diagnosis #Management ... #Hematology #Rheumatology
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
BEE Syndromes - ... Non-inflammatory ... MRI lesions and clinical ... #Syndromes #neurology ... noninflammatory #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
mucositis - Rash ... : - Ocular inflammatory ... purpura: strong sign ... #diagnosis #rheumatology ... #classification
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease ... (25-75%): Inflammatory ... skin injury) • Neurologic ... #signs #symptoms ... #rheumatology #
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... ischemia • Skin: Erythematous ... , mucositis • Rash ... : Ocular inflammatory ... #Diagnosis #Rheumatology