14 results
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
BEE Syndromes - ... erythematosus ... ANCA-associated vasculitides ... #Syndromes #neurology ... differential #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... photosensitivity, inflammatory ... Classification: ... rashErythematous ... Frank nephritis (hypertension
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... , Vasculitis, Purpura ... Demyelinating syndromes ... #systemic #erythematosus ... #signs #symptoms
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
mucositis - Rash ... : - Ocular inflammatory ... purpura: strong sign ... , and SLE) • Urinalysis ... #rheumatology #classification
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
clinically significant ... (SLE), Systemic ... : Lupus (SLE), Systemic ... Drug-Induced, Inflammatory ... rheumatology #diagnosis #differential
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
(SLE) Clinical ... Demyelinating Syndrome ... Cerebrovascular Disease ... Treatment: • Inflammatory ... #SLE #CNS #neurology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... as SLE, atherosclerotic ... purpura: Strong sign ... , mucositis • Rash ... : Ocular inflammatory
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease ... (25-75%): Inflammatory ... skin injury) • Neurologic ... ) Differential Diagnosis ... #signs #symptoms
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
erythematosus ... Petechial or purpuric rash ... lupus erythematosus ... [SLE], AOSD) • ... #Diagnosis #Management
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
- Workup and Differential ... evaluation should be ... 109 mm Hg) with clinical ... Coarctation of aorta, Vasculitis ... Renal parenchymal disease