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diagnosis rheumatology lupus activation algorithm amyotrophic ana antibodies antinuclear behcet disorders gca giantcell hematology laboratory macrophage mas patterns rheumatic rheumatoid
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... arthritis, weight ... rash • Erythematous ... , rheumatoid arthritis ... Arthritis: •
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... , Vasculitis, Purpura ... of hip (rare), Arthritis ... #systemic #erythematosus ... #signs #symptoms
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
lupus erythematosus ... Juvenile Idiopathic Arthritis ... lupus erythematosus ... lupus erythematosus ... Juvenile Idiopathic Arthritis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
and often causes arthritis ... Glomerulonephritis, arthritis ... ischemia - Skin: erythematous ... , arthritis LARGE ... lupus erythematosus
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... , Reactive arthritis ... Ocular melanoma • Arthritis ... Arthritis, AS Treatment ... #signs #symptoms
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
as SLE, atherosclerotic ... GCA (Giant Cell Arteritis ... ischemia • Skin: Erythematous ... , arthritis Primary ... and often causes arthritis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
juvenile idiopathic arthritis ... erythematosus ... idiopathic arthritis ... lupus erythematosus ... [SLE], AOSD) •
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
- Clinical Presentation ... Hyperreflexia develops later ... signs and/or symptoms ... #diagnosis #management ... #neurology #differential
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
neurological lesion: Clinical ... and signs below ... Inflammatory: ... - SLE, Scleroderma ... , Systemic sclerosis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
• Septic arthritis ... lupus erythematosus ... Arthritis: • ... when rheumatoid arthritis ... #Rheumatoid #Arthritis
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