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diagnosis rheumatology erythematosus lupus symptoms algorithm treatment activation ana antibodies antinuclear arthritis arthropathies arthropathy behcet cerebritis cns cord cryoglobulinemia cryoglobulins
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
BEE Syndromes - ... erythematosus ... optica spectrum disorder ... #Syndromes #neurology ... differential #diagnosis
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
- (Reiter’s syndrome ... psoriasis (7-30%) • Inflammatory ... Lupus Erythematosus ... (SLE), should have ... like “butterfly rash
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... photosensitivity, inflammatory ... Classification: ... rash • Erythematous ... • Transverse Myelitis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... , Vasculitis, Purpura ... of hip (rare), Arthritis ... #systemic #erythematosus ... #signs #symptoms
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
clinically significant ... (SLE), Systemic ... : Lupus (SLE), Systemic ... Lymphoproliferative Disorders ... Drug-Induced, Inflammatory
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... : - Ocular inflammatory ... purpura: strong sign ... , and SLE) • Urinalysis ... #rheumatology #classification
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
(SLE) Clinical ... Demyelinating Syndrome ... Cerebrovascular Disease ... Treatment: • Inflammatory ... #SLE #CNS #neurology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... • Autoimmune diseases ... : - 10% SLE or ... lupus erythematosus ... diagnosis #types #classification
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... (25-75%): Inflammatory ... skin injury) • Neurologic ... ) Differential Diagnosis ... #signs #symptoms
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... as SLE, atherosclerotic ... purpura: Strong sign ... , mucositis • Rash ... : Ocular inflammatory
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