14 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
for Hemolysis - ... usually IgG) (e.g. lupus ... lymphoproliferative disorders ... #differential # ... diagnosis #hematology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... 69% - Malar rash ... Lymphadenopathies 7% - Hemolytic ... Diagnosis and Lupus ... #signs #symptoms
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... rashErythematous ... alopecia Differential ... Diagnosis: • ANCA-associated ... #Diagnosis #Rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Platelet Disorders ... Diagnosis and Workup ... procedures - Infection ... Diagnosis #Causes ... #Workup #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... #Diagnosis #hematology ... #rheumatology #
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
diseases - HIV infection ... Schistosomiasis - Chronic hemolytic ... anemia - Persistent ... #Diagnosis #Differential ... #Causes
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... , Infection, Autoimmune ... , Interstitial Pulmonary ... #patterns #rheumatology ... #diagnosis #differential
Causes of Purpura or Easy Bruising in Children

Platelet count reduced, i.e. thrombocytopenia
 - Increased platelet destruction
(systemic lupus ... erythematosus) ... other severe infections ... peds #pediatrics #diagnosis ... #differential #
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism

In contrast to the
Pulmonary Embolism ... disorders, although ... erythematosus. ... life-threatening causes ... #Signs #Presentation
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often causes arthritis ... mucositis - Rash ... LFT • ESR • ANA ... #diagnosis #rheumatology ... #classification