24 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
loop of Henle Gitelman ... Fanconi #Bartter #Gitelman ... #Localization #Nephron ... #Defects #Pathophysiology ... #Nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... Gitelman Syndrome ... delivery to distal nephron ... #Syndrome #Pathophysiology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
mimics complete • Central ... and lower motor neuron ... #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
Mechanisms of nephron ... in cardiorenal syndrome ... #cardiorenal #syndrome ... #Mechanisms #pathophysiology ... #nephrology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
- Bartter - Gitelman ... SIGNS: • Muscle ... • AMS (altered mental ... Diagnosis #Algorithm #Pathophysiology ... #Nephrology #Chloride
Incomplete spinal cord syndromes (ISCS)
 • Central - Small Lesion - Suspended sensory deficit, classic cape
Incomplete spinal cord syndromes ... (ISCS) • Central ... positive Romberg sign ... Incomplete #spinalcord #syndromes ... #diagnosis #neurology
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... disc herniation (central ... lumbar spine Signs ... #CaudaEquina #Syndrome ... #MSK #pathophysiology
NINDS Diagnostic Criteria for Guillain Barre Syndrome 
Features Required for Guillain-Barré Syndrome:
 • Progressive muscle weakness
Guillain Barre Syndrome ... sensory symptoms or signs ... sensory level • Central ... nervous system signs ... diagnosis #criteria #neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Upper Motor Neuron ... • Acute stroke syndromes ... lesions of the central ... Lack of UMN/LMN signs ... Differential #Diagnosis #neurology
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... - Lower motor neuron ... - Upper motor neuron ... dysfunction Central ... differential #diagnosis #neurology