30 results
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing
TDD in units of insulin = N
Estimating the Total ... Dose (TDD) of Insulin ... #dosing #estimation ... #pharmacology #endocrinology ... #diabetes #DM2
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Pathophysiology ... deficit: - Type I DM ... - Type II DM ... #dka #hhs #pathophysiology ... #comparison #endocrinology
Pathophysiology and Effects of Insulin Deficiency

#Insulin #Deficiency #DKA #Ketoacidosis #Diabetes #Pathophysiology #Endocrinology
Pathophysiology ... and Effects of Insulin ... Deficiency #Insulin ... Ketoacidosis #Diabetes #Pathophysiology ... #Endocrinology
Diabetes Medications Summary Table
Insulin
Lifestyle modifications
Metformin
Sulfonylureas
GLP-1 receptor agonists - ↓ major adverse CV events
TZDs
DPP-4 inhibitors
SGLT2 inhibitors -
Diabetes Medications Summary ... Table Insulin ... comparison #management #endocrinology ... #dm2
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
- Pharmacology Summary ... cells, triggering insulin ... #Pharmacology #Summary ... #DM2 #diabetes ... #endocrinology
Management of type 2 diabetes in adults: summary of updated NICE guidance
#diabetes #type2 #DM2 #management #NICE
diabetes in adults: summary ... diabetes #type2 #DM2 ... #medications #insulin
Pathogenesis of Diabetic Ketoacidosis - Insulin deficiency or severe insulin insensitivity 

#DKA #Pathophysiology #Endocrinology #Diabetes #Ketoacidosis
Ketoacidosis - Insulin ... deficiency or severe insulin ... insensitivity #DKA #Pathophysiology ... #Endocrinology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology Summary ... • Increases insulin-mediated ... #Pharmacology #Summary ... #DM2 #diabetes ... #endocrinology
INSULIN CONVERSION

Total daily dose of insulin (TDD) =
INSULIN CONVERSION ... daily dose of insulin ... & most type 2 DM ... rules of thumb for estimating ... hyperglycemia #dm2
Summary and links to five landmark trials of intensive control vs standard therapy in DM2:

 UKPDS
Summary and links ... standard therapy in DM2 ... VisualAbstract #Endocrinology ... PrimaryCare #Diabetes #DM2