21 results
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing
TDD in units of insulin = N
Estimating the Total ... Dose (TDD) of Insulin ... TDD in units of insulin ... #dosing #estimation ... endocrinology #diabetes #DM2
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Pathophysiology ... HHS) Absolute Insulin ... deficit: - Type I DM ... - Type II DM ... #dka #hhs #pathophysiology
INSULIN CONVERSION

Total daily dose of insulin (TDD) =
INSULIN CONVERSION ... daily dose of insulin ... & most type 2 DM ... rules of thumb for estimating ... hyperglycemia #dm2
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
minutes) Decrease potassium ... Fluids Shift potassium ... intracellularly: • Insulin ... Sodium bicarbonate Potassium ... #nephrology
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
ATP-sensitive potassium ... cells, triggering insulin ... Pharmacology #Summary #DM2
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
K+ into cells: Insulin ... Algorithm #causes #potassium ... #low #pathophysiology
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
HCTZ) 5) Potassium-sparing ... spironolactone) #Pathophysiology ... #Nephrology #Nephron
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Poorly controlled DM ... • Recent IV potassium ... paralysis - Insulin ... diagnosis #causes #potassium ... #high #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Poorly controlled DM ... • Recent IV potassium ... paralysis - Insulin ... diagnosis #causes #potassium ... #high #nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
the basis of the potassium-to-creatinine ... Administration of inulin ... hypokalemia #urine #potassium ... algorithm #diagnosis #nephrology