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diagnosis management lupus differential algorithm disorders druginduced summary biopsy causes cell comparison dil eosinophil eosinophilia erythematosus hemophagocytic hlh indications lymphohistiocytosis
Initial triage of the neutropenic adult - Algorithm for the evaluation and treatment of adult patients
Algorithm for the evaluation ... and treatment of ... neutropenia #Algorithm #workup ... #diagnosis #hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... • Immunologic Workup ... life-threatening • Treatment ... • Evolution: ... Management #Summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... cutaneous-DIL • Evolution ... • Immunologic Workup ... • Evolution: ... comparison #table #rheumatology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
during medical evaluation ... or workup for specific ... 1,500 cells/µL Workup ... glucocorticoid treatment ... Differential #diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... test, ANA (e.g., SLE ... - Bone marrow evaluation ... Diagnosis #Causes #Workup ... #hematology
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
in 10 to 40% of SLE ... renal histological evaluation ... Nephritis #Management #treatment ... #management #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Autoimmune diseases: SLE ... Unknown cause Treatment ... inhibitors under evaluation ... diagnosis #management #treatment ... #summary #rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
is rare in DIL, SCLE-DIL ... • Immunologic Workup ... cutaneous-DIL • Evolution ... DrugInduced #Lupus #DIL #rheumatology ... #diagnosis #treatment
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Diagnostic Evaluation ... Bone marrow Treatment ... Oncology #Diagnosis #Workup ... #Hematology
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