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diagnosis rheumatology syndrome algorithm druginduced oncology sle acquired activation adultonset alopecia antinxp2 antinxp2dm bleeding bruising central classification comparison dermatomyositis dil
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... infection Malar rash ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... #skin #rashes #differential
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Manifestations: Malar rash ... life-threatening • Treatment ... of SLE • Evolution ... : Chronic disease ... #Summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... Manifestations: Malar rash ... of SLE • Evolution ... : Chronic disease ... #diagnosis #management
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... arthritis, Skin rash ... fraction < 20% Differential ... #diagnosis #management ... #treatment #rheumatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
extensive skin rash ... Resolution > 15 ... days Differentials ... : symptomatic treatment ... DRESS #Syndrome #dermatology
Maculopapular Rashes - THE ALGORITHMIC APPROACH The term maculopapule is a portmanteau, a combination of macule and
febrile have a wide differential ... assessed for Lyme disease ... have a broader differential ... require emergent evaluation ... #Diagnosis #Dermatology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Diagnosis and Management ... thrombocythemia), Autoimmune disease ... Syndrome #Diagnosis #Management ... #treatment #hematology ... #differential
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... Petechial or purpuric rash ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Eosinophilic Gastroenteritis: Treatment Options Based on Severity of the Disease Mild: • Trial of PPI • Trial
Gastroenteritis: Treatment ... Severity of the Disease ... Concern for HES: • Hematology ... consult for evaluation ... #management #gastroenterology
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH These rashes can be especially challenging and are associated with devastating differential
in vasculitic diseases ... require emergent evaluation ... petechial or purpuric rash ... #Diagnosis #Dermatology ... Purpural #Purpuric #Rash
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