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diagnosis hematology oncology blood myelodysplastic reactions syndrome activation adjusted age anemia challenges comparison criticalcare ddimer differential dimer fluid macrophage myelodysplasia
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... myelodysplastic syndrome (MDS ... Hypocellular/Hypoplastic MDS ... abnormalities typical for MDS ... #diagnosis #management
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... dys- (abnormal) -plastic ... old, ~10,000 new cases ... Myelodysplastic #Syndrome #MDS ... #treatment #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes (MDS ... platelets) • MDS ... precursors MDS ... • Anemia • Aplastic ... chemotherapy #MDS
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
severe thrombocytopenia ... due to marrow aplasia ... by Nick Mark MD ... Transfusions #diagnosis #management ... #hematology #reactions
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Activation Syndrome (MAS ... manifestation of MAS ... Sepsis • Drug-induced ... Fibrin degradation products ... Plasma exchange #MAS
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
severe thrombocytopenia ... due to marrow aplasia ... infographic by Nick Mark MD ... Transfusion #diagnosis #management ... #hematology #reactions
D-dimer Plasma D-dimer is a product of clot breakdown, released upon degradation of polymerized, crosslinked fibrin. Elevated
Plasma D-dimer is a product ... age, which can cause ... yrs of age - Example ... Satyendra Dhar, MD ... pathophysiology #hematology
Fluid Responsiveness and Fluid Tolerance Testing - OnePager Summary Fluid resuscitation can be beneficial when required or
, resulting in reduced ... : Measures CVP as ... cardiac output causes ... by Nick Mark MD ... comparison #challenges #management
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