30 results
Lactic Acidosis - Overview and Pathophysiology
Lactic acid is an endogenous substrate for gluconeogenesis, that is constantly
- Overview and Pathophysiology ... Lactic acid is an endogenous ... with exercise/activity ... why LR does not cause ... #classification
The interferon (IFN) signature: what’s the point? How to use it in clinical practice?

Characterizing activity of
Characterizing activity ... pathway in the clinic ... understanding of pathophysiology ... To propose new classifications ... signature #diagnosis #management
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Diagnosis and Management ... extrapulmonary cases ... Clinical Signs ... of active pulmonary ... decreased reflexes Pathophysiology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... increased B-cell activity ... renal failure Clinical ... Sarcoidosis #Diagnosis #Management
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... interferes with the activity ... presentation - Clinical ... also includes symptoms ... Toxicology #Diagnosis #Management
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Pathogenesis and clinical ... Poliomyelitis Activity ... Trendelenburg #Gait #pathophysiology ... #causes #symptoms
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Diagnosis and Management ... Summary Pathophysiology ... epidermis from dermis Clinical ... Signs/Symptoms/ ... - Erosions and crusts
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... = nonspecific (nausea ... Maternal Support - Critical ... #pathophysiology
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
fatigue despite clinical ... Pearls: • IDA and active ... diet/deficiency symptoms ... /other causes • ... Algorithm #diagnosis #management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Active: Symptomatic ... Tuberculosis: • Endogenous ... characteristic features Clinical ... TB #Diagnosis #Management