48 results
Lactic Acidosis - Overview and Pathophysiology
Lactic acid is an endogenous substrate for gluconeogenesis, that is constantly
Lactic acid is an endogenous ... with exercise/activity ... of underlying disease ... why LR does not cause ... Acidosis #types #differential
Central Retinal Vein Occlusion (CRVO)
 - Pathophysiology not fully understood; possibly due to thrombus located in
Occlusion (CRVO) - Pathophysiology ... retinal vascular disease ... (Most common cause ... retinopathy) #Clinical ... #Ophthalmology
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
although hepatic causes ... decompensated liver disease ... - Significant endogenous ... deficiency #Ammonia #Pathophysiology ... Hyperammonemia #Differential
Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Hypertension - BP > 140/90 (>130/80 for DM)
Hypertensive urgency
Hypertension - Differential ... based on repeat clinic ... Renal Parenchymal Diseases ... Steroids (Cushing's, exogenous ... Secondary #Nephrology #Differential
Important Causes of Diplopia 
TIER 1-CRITICAL
Basilar artery thrombosis, Botulism, Basilar meningitis, Aneurysmn
TIER 2-EMERGENT:
Vertebral dissection, Myasthenia gravis,
Important Causes ... Diplopia TIER 1-CRITICAL ... myopathy (Graves disease ... mass #Diplopia #differential ... #diagnosis #ophthalmology
Osgood-Schlatter Disease - MSK Radiology
Imaging Findings:
 • Infrapatellar fat-pad edema with loss of the patellar tendon
Osgood-Schlatter Disease ... : • Active adolescents ... exacerbated with activity ... tibial tuberosity Differential ... #mri #clinical
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Chronic kidney disease ... Tuberculosis: • Endogenous ... characteristic features Clinical ... TB #Diagnosis #Management
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
structural heart disease ... syncope (ruling out differential ... further guide management ... should be guided by clinical ... the underlying disease
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... extrapulmonary cases ... Clinical Signs ... signs/symptoms of active ... decreased reflexes Pathophysiology
The interferon (IFN) signature: what’s the point? How to use it in clinical practice?

Characterizing activity of
Characterizing activity ... pathway in the clinic ... understanding of pathophysiology ... classifications for diseases ... signature #diagnosis #management