178 results
Fever - Pyrogen Pathophysiology

EXOGENOUS PYROGEN
 • Bacteria: Lipopolysaccharide components, peptidoglycans and muramyl peptide derivatives, Toxins
 •
Fever - Pyrogen Pathophysiology ... EXOGENOUS PYROGEN ... components Exogenous ... vasculature via: • Active ... Fever #Fever #Pathophysiology
Staging of Skin Mottling

Mottling is less sensitive, but more specific for hypoperfusion and elevated mortality (figure
Mottling suggests active ... endogenous vasoconstriction ... not additional exogenous ... Mottling #Staging #Clinical ... Diagnosis #Stages #Clinical
Rigors And Bacteremia - Overview

• Rigors are a response to the release of cytokines and prostaglandins
PATHOPHYSIOLOGY: ... → Exogenous Pyrogen ... Pyrogen) → Endogenous ... vasculature via: • Active ... Rigors #Bacteremia #Pathophysiology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Succinylcholine) • Exogenous ... differential #diagnosis #pathophysiology ... #pharmacology #
Benzodiazepines: Mechanism of Action and Side Effects
 • Decr spinal cord activity -> Muscle relaxant
Decr spinal cord activity ... amygdala-centered circuit activity ... cerebral cortex activity ... Benzodiazepines #Psychiatry #Pharmacology ... #pathophysiology
Lactic Acidosis - Overview and Pathophysiology
Lactic acid is an endogenous substrate for gluconeogenesis, that is constantly
- Overview and Pathophysiology ... Lactic acid is an endogenous ... with exercise/activity ... why LR does not cause ... differential #diagnosis #pathophysiology
Arachidonic acid pathway and drugs which affect it.

#Pharmacology #Pathophysiology #ArachidonicAcid #Pathways #COX #Prostaglandins #Prostacyclins #Leukotrienes #Synthesis

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#Pharmacology #Pathophysiology ... Recommended Text: Clinical ... Pharmacology Made
Glucagon: Bypassing β-Blockade

Glucagon pathophysiology and clinical applications in anaphylaxis and beta-blocker overdose

#Toxicology #Pharmacology #Pathophysiology #Glucagon #BetaBlocker
β-Blockade Glucagon pathophysiology ... and clinical applications ... #Toxicology #Pharmacology ... #Pathophysiology
Systemic Glucocorticoid Dose Equivalents. 

Note: approximate equivalent dose is based on anti-inflammatory potency. Fludrocortisone is not
mineralocorticoid activity ... anti-inflammatory activity ... chemotherapy induced nausea ... (postoperative nausea ... #Equivalents #Pharmacology
Hydroxyurea - Pathophysiology and Benefits in Sickle Cell Disease
 • Decreases number of pain crises (
Hydroxyurea - Pathophysiology ... number of pain crises ... Benefits #SickleCell #pathophysiology ... #pharmacology