498 results
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
liver or kidney disease ... smoking, etoh, decr activity ... #Osteoporosis #pathophysiology ... #signs #symptoms ... #diagnosis
Staging of Skin Mottling

Mottling is less sensitive, but more specific for hypoperfusion and elevated mortality (figure
Mottling suggests active ... not additional exogenous ... Mottling #Staging #Clinical ... #Diagnosis #Stages ... #Clinical
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease ... Pathophsiology ... ß-glucocerebrosidase activity ... in GBA1 gene Clinical ... #Symptoms
Hashitoxicosis

‘Leakage’ symptoms of active Hashimoto’s disease

- Hashitoxicosis (Htx) can occur during the initial hyperthyroid stage in
Hashitoxicosis ‘Leakage’ symptoms ... thyroiditis that causes ... ‘Leakage’ symptoms ... Endocrinology #Diagnosis ... #Pathophysiology
Headache Differential - Primary vs Secondary
A vast number of diseases can cause a headache. We divide
vast number of diseases ... can cause a headache ... headaches are caused ... by various exogenous ... disorders #Diagnosis
Rigors And Bacteremia - Overview

• Rigors are a response to the release of cytokines and prostaglandins
PATHOPHYSIOLOGY: ... → Exogenous Pyrogen ... vasculature via: • Active ... Rigors #Bacteremia #Pathophysiology ... InfectiousDiseases #Diagnosis
Alcohol Withdrawal Summary

Pathophysiology, Symptoms, Cause, Course, Management 

#Diagnosis #Management #Pathophysiology #Alcohol #Withdrawal #Symptoms
Withdrawal Summary Pathophysiology ... , Symptoms, Cause ... Management #Diagnosis ... #Management #Pathophysiology ... Alcohol #Withdrawal #Symptoms
Causes of Abnormal Genital Bleeding - Differential Diagnosis Algorithm
Non-Gynecologic:
 • Medical (e.g. coagulopathy, liver disease, renal
Causes of Abnormal ... - Differential Diagnosis ... , renal disease) ... • Polyp • Exogenous ... #Algorithm #Causes
Hyperthyroidism - Differential Diagnosis Algorithm
High/Normal Radioiodine Uptake
 - Autoimmune Thyroid Disease:
    • Grave's
- Differential Diagnosis ... Autoimmune Thyroid Disease ... • Grave's Disease ... Radiation - Exogenous ... endocrinology #causes
Lactic Acidosis - Overview and Pathophysiology
Lactic acid is an endogenous substrate for gluconeogenesis, that is constantly
Lactic acid is an endogenous ... with exercise/activity ... of underlying disease ... why LR does not cause ... #differential #diagnosis