84 results
Lactic Acidosis - Overview and Pathophysiology
Lactic acid is an endogenous substrate for gluconeogenesis, that is constantly
- Overview and Pathophysiology ... Lactic acid is an endogenous ... with exercise/activity ... why LR does not cause ... #classification
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Causes of Metabolic ... ectopic ACTH) • Exogenous ... dehydrogenase activity ... loop diuretics actively ... Differential #Diagnosis #Causes
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can activate ... • They can cause ... : • Clinical triad ... diagnosis #types #classification ... #rheumatology #
Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Hypertension - BP > 140/90 (>130/80 for DM)
Hypertensive urgency
based on repeat clinic ... • Nephritic syndrome ... Excess: • Conn's syndrome ... Licorice • Liddle's syndrome ... Steroids (Cushing's, exogenous
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
although hepatic causes ... namely, the many causes ... - Significant endogenous ... rare): - Reye syndrome ... deficiency #Ammonia #Pathophysiology
The interferon (IFN) signature: what’s the point? How to use it in clinical practice?

Characterizing activity of
How to use it in clinical ... Characterizing activity ... pathway in the clinic ... understanding of pathophysiology ... To propose new classifications
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Pathogenesis and clinical ... exposure to allergen causes ... harmful -> Th Cells activate ... Stevens-Johnson Syndrome ... Allergy #Immunology #pathophysiology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
39 C this is a clinical ... production • Actively ... maintained fever CAUSES ... • Serotonin syndrome ... #Differential #Causes
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... increased B-cell activity ... renal failure Clinical ... symptoms are not caused ... • Heerfordt syndrome
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... Leukostasis: • Pathophysiology ... high WBC count cause ... : • Pathophysiology ... diagnosis #management #hematology