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diagnosis management hematology neurology hemophagocytic hlh lymphohistiocytosis als amyotrophic anesthesia anesthesiology cerebritis checklist classification cns cryoglobulinemia cryoglobulins differential erythematosus hemeonc
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... CNS #neurology #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... : • Pathophysiology ... diagnosis #management #hematology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
39 C this is a clinical ... Treatment depends ... production • Actively ... maintained fever CAUSES ... hyperthermia crisis (late sign
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can activate ... • They can cause ... : • Clinical triad ... (e.g. systemic lupus ... classification #rheumatology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
increased B-cell activity ... renal failure Clinical ... symptoms are not caused ... skin (16-32%): lupus ... Diagnosis #Management #Signs
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... Diagnosis: HLH signs ... absent NK cell activity ... #hematology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Prevalence: 1-2 cases ... Pathophysiology ... Clinical Manifestations ... continuous motor unit activity ... Treatment: •
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... Excessive glutamate activity ... - Causes progressive ... diagnosis column Treatment ... by decreasing activity
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... Adenocarcinoma Treatment ... muscarinic agonists • Active ... #Rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
caused by uncontrolled ... Clinical Presentation ... • Common Signs ... Pathophysiology ... absent NK-cell activity
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