14 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Kasabach-Merritt syndrome ... Pigmented Purpuric Dermatosis ... Gardner-Diamond syndrome ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Neutrophilic dermatoses ... Rare Disorder: ... - Rash: multiple ... Causes: - Idiopathic ... #diagnosis #dermatology
Ketosis Disorders
Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
Ketosis Disorders ... pt will produce endogenous ... syndrome ... ketoacidosis (DKA) - caused ... Glucosuria causes
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm

HYPOPIGMENTATION
Diffuse Congenital - Generalized hypopigmentation of
Disorders of Pigmentations ... sclerosis (white "ash ... McCune Albright syndrome ... #skin #dermatology ... Diagnosis #Algorithm #causes
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can activate ... immune system, leading ... • They can cause ... Cryoglobulins Cause ... rheumatoid factor activity
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
reaction -> Benign Rash ... Stevens-Johnson Syndrome ... relapse of bipolar disorder ... of dopaminergic activity ... Systemic effect -> Nausea
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
Willebrand factor activity ... ristocetin cofactor activity ... von Willebrand syndrome ... discern these causes ... Differential #Diagnosis #Hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
chronic inflammatory disorder ... Autoinflammatory disorder ... and neutrophilic dermatoses ... Rule out other causes ... diagnosis #management #Dermatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... skin that are caused ... by bleeding (petechiae ... Neutropenia • Platelet Disorders ... #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Tyrosine Kinase activity ... -> AML: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology