7 results
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Neutrophilic dermatoses ... - Rash: multiple ... Causes: - Idiopathic ... #diagnosis #dermatology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Tyrosine Kinase activity ... -> AML: Blast crises ... PLT: Petechiae, bruising ... • Tumor lysis syndrome ... #Oncology #Diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
IL-1 and IL-6, leading ... manifestations: from easy bruising ... purpura to mucosal bleeding ... Petechial or purpuric rash ... Diagnosis #Management #Hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... Easy or unusual bruising ... by bleeding (petechiae ... #diagnosis #hematology ... #oncology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
Bleeding and Bruising ... Willebrand factor activity ... von Willebrand syndrome ... discern these causes ... #Bruising #Hemostasis
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
ecchymoses, mucosal bleeding ... and petechiae Causes ... (MDS) (normal or ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... 24-48 h and ANC rising ... Simultaneous clotting and bleeding ... Treat underlying cause ... - CRS: fever, rash