17 results
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Mucocutaneous Manifestations ... cytokines -> localized inflammatory ... hair follicles -> causes ... decr release and activity ... pathophysiology #diagnosis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... GPA causes disease ... Rarely dominate the clinical ... Maculopapular rash ... #rash #diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
release of pro-inflammatory ... Fever is the main clinical ... manifestation of ... Petechial or purpuric rash ... Activation #Syndrome #Diagnosis
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... auricular papules Clinical ... #rheumatology #dermatology ... #diagnosis
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
dogs & latter can cause ... gram-negative bacillus cause ... due to profound inflammatory ... the key to the diagnosis ... #dermatology #clinical
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... : • A clinical ... out other causes ... Osteoarticular manifestations ... #management #Dermatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... or low • ESR (Inflammatory ... • PET scan - activity ... lymph node biopsy (diagnostic ... #oncology #management
Amyloidosis - Summary
Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Clinical suspicion ... Amyloidosis Clinical ... Manifestations: ... Dystrophy Heme: • ↓ activity ... hypoadrenalism • Nausea
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
(COVID-19) • Inflammatory ... Cryofibrinogenemia Clinical ... Manifestations ... : • + Clinical ... cryoglobulins • Negative causes
Acute Generalized Exanthematous Pustulosis (AGEP)

AGEP is largely a clinical diagnosis based on classical skin findings in
AGEP is largely a clinical ... T-cell-mediated inflammatory ... Causes? ... Manifestations generally ... Exanthematous #Pustulosis #Dermatology