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diagnosis algorithm causes nephrology management workup hyponatremia clinical table hypokalemia pathophysiology metabolic secondary stroke syndrome aki disorders kidney potassium treatment
Fever - Pyrogen Pathophysiology EXOGENOUS PYROGEN • Bacteria: Lipopolysaccharide components, peptidoglycans and muramyl peptide derivatives, Toxins •
Pathophysiology EXOGENOUS ... components Exogenous ... , IFN, IL-6 ENDOGENOUS ... vasculature via: • Active ... organs CNS - Endogenous
Hypercortisolism (Cushing syndrome) - Simplified Differential Diagnosis Algorithm Exogenous (ACTH-independent) Endogenous • ACTH-dependent: - ACTH-secreting
) - Simplified Differential ... Diagnosis Algorithm Exogenous ... ACTH-independent) Endogenous ... Cushings #syndrome #Differential
Workup for Hyperphosphatemia - Differential Diagnosis Framework Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
Hyperphosphatemia - Differential ... Phosphate Load: • Exogenous ... Fosphenytoin • Endogenous ... Hyperphosphatemia #Differential ... Workup #phosphate #nephrology
Staging of Skin Mottling Mottling is less sensitive, but more specific for hypoperfusion and elevated mortality (figure
Mottling suggests active ... endogenous vasoconstriction ... not additional exogenous
Polyuria - Differential Diagnosis Algorithm Urine Output > 3L /day Water Diuresis (Urine Osm <100 mOsm/kg) • Primary
Polyuria - Differential ... • Azotemia • Exogenous ... #Polyuria #Differential ... Algorithm #causes #nephrology
Rigors And Bacteremia - Overview • Rigors are a response to the release of cytokines and prostaglandins
PATHOPHYSIOLOGY: → Exogenous ... pro-inflammatroy mediators (Endogenous ... Pyrogen) → Endogenous ... vasculature via: • Active ... circumventricular organs CNS: Endogenous
Thyroid Disorders - Differential Diagnosis Algorithm Hypothyroidism: • Hasimoto’s • Radioactive Iodine • Hypopituitarism • Iodine
Thyroid Disorders - Differential ... Thyroiditis • Exogenous ... Thyroid #Disorders #Differential
Polyuria - Differential Diagnosis Solute Diuresis • Na intake/saline • Glucosuria: Hyperglycemia, SGLT-2 inhibitors • Urea: Exogenous
Polyuria - Differential ... inhibitors • Urea: Exogenous ... #Polyuria #Differential
Headache Differential - Primary vs Secondary A vast number of diseases can cause a headache. We divide
Headache Differential ... caused by various exogenous ... #Diagnosis #Differential
Hypokalemia Differential Diagnosis Algorithm Hypertensive: • High Al, Low R - Primary aldosteronism • High Al, High
Hypokalemia Differential ... Pseudo-hyperaldosteronism: exogenous ... #Hypokalemia #Differential ... Diagnosis #Algorithm #nephrology
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