265 results
Fever - Pyrogen Pathophysiology

EXOGENOUS PYROGEN
 • Bacteria: Lipopolysaccharide components, peptidoglycans and muramyl peptide derivatives, Toxins
 •
Pathophysiology EXOGENOUS ... components Exogenous ... , IFN, IL-6 ENDOGENOUS ... vasculature via: • Active ... organs CNS - Endogenous
Staging of Skin Mottling

Mottling is less sensitive, but more specific for hypoperfusion and elevated mortality (figure
Mottling suggests active ... endogenous vasoconstriction ... not additional exogenous ... Mottling #Staging #Clinical ... Diagnosis #Stages #Clinical
Cephalosporins 
Cephalosporins are bactericidal beta-lactam antibiotics derived from the fungus Acremonlum— they disrupt peptidoglycan formation in
They have no activity ... predominantly active ... progressively more active ... gram-positive activity ... Classification #pharmacology
Rigors And Bacteremia - Overview

• Rigors are a response to the release of cytokines and prostaglandins
PATHOPHYSIOLOGY: → Exogenous ... pro-inflammatroy mediators (Endogenous ... Pyrogen) → Endogenous ... vasculature via: • Active ... circumventricular organs CNS: Endogenous
Clinical Pharmacologic Properties of Antiarrhythmic Drugs

#Antiarrhythmic #Drugs #Medications #Pharmacology #Cardiology #Table #Effects
Clinical Pharmacologic ... #Medications #Pharmacology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Succinylcholine) • Exogenous ... pathophysiology #pharmacology
Pharmacologic prophylaxis of VTE in selected clinical scenarios.

Enoxaparin 
Dalteparin 
Fondaparinux 
Dabigatran 
Unfractionated Heparin
Warfarin 
Aspirin 

#prophylaxis #VTE
Pharmacologic prophylaxis ... VTE in selected clinical ... #indications #pharmacology
Benzodiazepines: Mechanism of Action and Side Effects
 • Decr spinal cord activity -> Muscle relaxant
Decr spinal cord activity ... amygdala-centered circuit activity ... cerebral cortex activity ... Benzodiazepines #Psychiatry #Pharmacology
Systemic Glucocorticoid Dose Equivalents. 

Note: approximate equivalent dose is based on anti-inflammatory potency. Fludrocortisone is not
mineralocorticoid activity ... anti-inflammatory activity ... #Equivalents #Pharmacology
Hemodynamic Effects of Long-Term Administration of Antihypertinsive Agents
Effects on Heart Rate, Cardiac Output, Total Peripheral Resistance,
, Plasma Renin Activity ... #medications #pharmacology