227 results
Fever - Pyrogen Pathophysiology

EXOGENOUS PYROGEN
 • Bacteria: Lipopolysaccharide components, peptidoglycans and muramyl peptide derivatives, Toxins
 •
Pathophysiology EXOGENOUS ... components Exogenous ... , IFN, IL-6 ENDOGENOUS ... vasculature via: • Active ... organs CNS - Endogenous
Staging of Skin Mottling

Mottling is less sensitive, but more specific for hypoperfusion and elevated mortality (figure
Mottling suggests active ... endogenous vasoconstriction ... not additional exogenous
Workup for Hyperphosphatemia - Differential Diagnosis Framework
Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
Phosphate Load: • Exogenous ... Fosphenytoin • Endogenous ... Workup #phosphate #nephrology
Rigors And Bacteremia - Overview

• Rigors are a response to the release of cytokines and prostaglandins
PATHOPHYSIOLOGY: → Exogenous ... pro-inflammatroy mediators (Endogenous ... Pyrogen) → Endogenous ... vasculature via: • Active ... circumventricular organs CNS: Endogenous
Rheumatoid Arthritis - ACR 2021 Guidelines
 - Low Disease Activity
 - Moderate to High Disease Activity
- Low Disease Activity ... to High Disease Activity ... Tapering DMARDs - Treatment ... Guidelines #management #treatment
Polyuria - Differential Diagnosis Algorithm
Urine Output > 3L /day
Water Diuresis (Urine Osm <100 mOsm/kg)
 • Primary
• Azotemia • Exogenous ... Algorithm #causes #nephrology
Diagnosis and Treatment of Common Causes of Pulseless Electrical Activity (PEA)

#Pulseless #Electrical #Activity #PEA #Differential #Diagnosis
Diagnosis and Treatment ... Pulseless Electrical Activity ... Pulseless #Electrical #Activity
Venous Thromboembolism Treatment Algorithm
Branch points: 
Active bleeding?  Active malignancy? Provoked?

- Dr. Joseph Shatzel
@Clotmaster

#Management #VTE #DVT
Thromboembolism Treatment ... Branch points: Active ... Active malignancy ... Thromboembolism #Treatment
Treatment Options for Lupus Nephritis

#Lupus #Nephritis #Treatment #management #nephrology
Treatment Options ... Lupus #Nephritis #Treatment ... #management #nephrology
Persistent UC Symptoms Despite 5-ASA Therapies
 • Assess for Drug Adherence
 • Disease Activity Assessment (bloody
Adherence • Disease Activity ... diarrhea correlates w active ... Escalate Treatment ... Colitis Escalate Treatment ... #5ASA #Refractory #Treatment