11 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... Principles of HIV-Associated ... • IRIS might ... should be based on clinical ... required until immune
Immune Reconstitution Inflammatory Syndrome (IRIS) - Pathophysiology
Risk factors:
 - Low CD4 count
 - Disseminated OI
 -
(IRIS) - Pathophysiology ... factors: - Low CD4 ... Uncoupling of innate and ... #IRIS #Pathophysiology ... #AIDS
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Inflammatory Syndrome ... treatment of HIV/AIDS ... be present: • AIDS ... pleural effusions, CNS ... Other Pathogens Associated
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Presentation (Pulmonary and ... : • Pauci-Immune ... vasculitis (IgA-associated ... Cryoglobulinemia) • Immune ... anti-ANCA ab, anti-GBM
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
HIV dementia Pathophysiology ... infects the CNS ... syndrome of HAD ... disorder #dementia #AIDS ... #Neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... transplantation CLINICAL ... the underlying pathophysiology ... Guillain #Barre #Syndrome ... diagnosis #management #neurology
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... experience Statin-Associated ... (GBS), systemic ... IU/I • SAMS clinical ... • If statin-associated
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Summary Acute AIDP ... Guillain-Barre Pathophysiology ... : • Immune response ... Paresthesias: Hands ... GQ1b IgG Antibody associated
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... fluctuations PRES-Associated ... Etiology: • Pathophysiology ... Seizures: Treat with AEDs ... diagnosis #management #neurology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
affects the skin, neurologic ... cognitive impairment, neurologic ... VASCULITIS: ANCA Associated ... GN Anti-GBM (10 ... chorioretinitis, CNS