18 results
diagnosis management differential hematology treatment barre cns erythematosus guillain hemophagocytic hiv hlh infections infectiousdiseases lupus lymphohistiocytosis systemic workup arthritis associated
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune ... non-Hodgkin lymphoma SLL ... Orange or Hep C Clinical ... • Richter’s Syndrome ... leukemia • Sezary syndrome
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... that disrupts immune ... Autoimmune diseases: SLE ... treatment #summary #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
) Clinical Manifestations ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... #CNS #neurology ... #rheumatology #
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
primary or secondary immune ... Autoimmune (Sjogren, SLE ... chemotherapy) • Genetic syndromes ... Common variable immune ... ICL #diagnosis #hematology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
Infection in HIV / AIDS ... should be based on clinical ... required until immune ... recovery (CD4-cell ... differential #diagnosis #AIDS
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Summary Acute AIDP ... Guillain-Barre Pathophysiology ... : • Immune response ... Guillain-Barre Clinical ... management #treatment #neurology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Non-autoimmune rheumatologic ... context of primary immune ... Clinical Features ... titers > 1:80 • CBC
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... transplantation CLINICAL ... the underlying pathophysiology ... Guillain #Barre #Syndrome ... diagnosis #management #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
brain PRES Clinical ... may precede the neurologic ... Etiology: • Pathophysiology ... Seizures: Treat with AEDs ... diagnosis #management #neurology
Humoral Immunity - Pathogenesis and Clinical Findings Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
Pathogenesis and Clinical ... present Ag to CD4 ... classical pathway (see ... amplitude of secondary immune ... Humoral #Immunity #pathophysiology
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