7 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... • IRIS might ... should be based on clinical ... required until immune ... Suspect in movement disorders
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Inflammatory Syndrome ... /AIDS patients ... be present: • AIDS ... initiation Clinical ... pleural effusions, CNS
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
dementia Pathophysiology ... and infects the CNS ... syndrome of HAD ... #dementia #AIDS ... #Neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Non-neuromuscular disorder ... Lack of UMN/LMN signs ... Polymyositis • Immune ... parainfluenza, Coxsackie, HIV ... Differential #Diagnosis #neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Summary Acute AIDP ... Guillain-Barre Pathophysiology ... : • Immune response ... Campylobacter jejuni - HIV ... management #treatment #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... that results in CNS ... Transverse Myelitis - Clinical ... • Bilateral signs ... simplex virus, HIV
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Clinical Presentation ... • Common Signs ... Pathophysiology ... of NK cells and CD8 ... malignancy, autoimmune disorder