19 results
diagnosis rheumatology management treatment dermatology differential lupus sle systemic classification hepatology hepatopulmonary neurology vasculitis abscess antimda5 antimda5dm bullous cerebritis chronic
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... and Management Summary ... 40, F:M 9:1 • Clinical ... Evolution: Chronic disease ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Malignancy (e.g. hematologic ... Clinical Features ... vein thrombosis Hematologic ... titers > 1:80 • CBC
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
(SLE) Clinical ... Demyelinating Syndrome ... Cerebrovascular Disease ... , PRES Pathophysiology ... autoantibodies that will cause
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
with edema • Erythematous ... violaceous macules and erythematous ... auricular papules Clinical ... severity of the disease ... #dermatology #diagnosis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... purpuric macules • Erythematous ... • Ulcerated, erythematous ... • Goodpasture syndrome
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... Drugs, Unknown cause ... management #treatment #summary ... #rheumatology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
Pott's Disease in ... and Management Summary ... extrapulmonary cases ... Clinical Signs ... decreased reflexes Pathophysiology
Bullous Pemphigoid - Diagnosis and Management Summary Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
and Management Summary ... Pathophysiology ... epidermis from dermis Clinical ... - Erosions and crusts ... not feasible CMC
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia Summary ... • They can cause ... : • Clinical triad ... • Autoimmune diseases ... systemic lupus erythematosus
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... ischemia - Skin: erythematous ... • Cogan Syndrome ... systemic lupus erythematosus ... Lab Tests: • CBC
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